Marina Pasca di Magliano, PhD
Maude T Lane Professor
Professor, Department of Surgery and Cell and Developmental Biology
Co-Leader, Cancer Biology Program, Comprehensive Cancer Center
Admissions Director, Cancer Biology Graduate Program
University of Michigan Medical School
Dr. Pasca di Magliano obtained her PhD at the Institute for Molecular Pathology in Vienna, Austria. She then joined the laboratory of Dr Matthias Hebrok at the University of California, San Francisco, for her postdoctoral training. The Hebrok laboratory studied embryonic signaling pathways in the development and disease of pancreatic islets; Dr Pasca di Magliano’s research branched out to pancreatic cancer, revealing a role for Hedgehog and Wnt signaling in this disease. Dr Pasca di Magliano joined the faculty at the University of Michigan in 2008, raising through the ranks to Full Professor in 2020. Her laboratory studies the role of oncogenic Kras, the hallmark mutation of pancreatic cancer, in the regulation of the establishment and maintenance of the pancreatic cancer stroma. Her work uses genetically engineered mice and human patient samples to characterize components of the microenvironment and their reciprocal interactions. In addition to running her laboratory, Dr Pasca di Magliano is the co-leader of the Cancer Biology research program for the Rogel Cancer Center at the University of Michigan and serves as Associate Director of the Cell and Molecular Biology graduate program and the Cancer Biology graduate program.