Yu-Ying He, PhD
Associate Professor of Medicine
Committee on Cancer Biology
Committee on Molecular Medicine
The University of Chicago
Our research addresses the fundamental questions: how normal cells respond to environmental carcinogens including UV radiation in sunlight and arsenic, and evolve into cancerous cells. In particular, our group focuses on the role of epitranscriptomics, epigenetics, and autophagy in regulating genomic integrity and cellular homeostasis and to investigate their impact on damage response, and their implications on skin cancer including squamous cancer and melanoma. Our long-term goal is to identify previously unrecognized,therapeutically accessible molecular regulatory networks that predict susceptibility to molecular and cellular damage and skin cancer, and improve our ability to prevent and treat these cancers.