Richard Pomerantz, PhD
Associate Professor, Medical Genetics and Molecular Biology
Associate Professor, Fels Institute for Cancer Research and Molecular Biology
Dr. Pomerantz’s laboratory is primarily interested in understanding how human DNA repair factors function and contribute to genome integrity and instability in normal and cancer cells, respectively. Current areas of interest include investigating mutagenic double-strand break repair pathways, such as alternative end-joining which contributes to genome instability and promotes the proliferation of cancer cells that are mutated in BRCA1/2. Because backup double-strand break repair pathways are essential for the proliferation of BRCA deficient cancer cells, we are interested in developing factors that promote these pathways as anti-cancer drug targets.