Isidore Rigoutsos , PhD
Director - Computational Medicine Center
Professor - Dept. of Pathology, Anatomy & Cell Biology | Dept. of Cancer Biology | Dept. of Biochemistry & Molecular Biology
Member - Sidney Kimmel Cancer Center
Sidney Kimmel Medical College at Thomas Jefferson University
Dr. Rigoutsos is the founding Director of the Computational Medicine Center at Jefferson. He holds Professor appointments in the Department of Pathology, Anatomy and Cell Biology, the Department of Cancer Biology and the Department of Biochemistry and Molecular Biology. He is also a member of Jefferson's Sidney Kimmel Cancer Center. Prior to joining Jefferson in 2010, Dr. Rigoutsos spent 18 years at IBM's Thomas J. Watson Research Center, where he worked on Computational Biology. From 2000 to 2010, and in parallel with his IBM tenure, Dr. Rigoutsos had a Visiting Faculty appointment at MIT's Dept. of Chemical Engineering where he taught graduate-level classes and summer professional courses in Bioinformatics. Dr. Rigoutsos is a Fulbright Scholar, and a Fellow of the American Institute for Medical and Biological Engineering since 2003. He is a member of the Editorial Boards of several academic journals that focus on Genomics, Biology, and Computational Biology.
Dr. Rigoutsos' involvement in the field of Computational Biology spans more than two decades. During this time, he has been developing algorithms that he used to study genomic phenomena and molecular interactions. He has authored or co-authored many peer-reviewed journal and conference articles in Computer Science and in Biology/Medicine, as well as many book chapters, and is a named inventor or co-inventor on several US Patents. Since 2002, Dr. Rigoutsos has been studying the molecular biology of short and long non-coding RNAs (microRNAs, pyknons, piRNAs, tRNAs etc.). In particular, he has been working on identifying short non-coding RNAs that are involved in post-transcriptional regulation, elucidating these short RNAs' interactions with other cellular transcripts, and determining how upsetting these interactions is linked to the onset and progression of human diseases.