The Big in Big Data

Philadelphia, PA US
November 7, 2018 to November 8, 2018


The Big in Big Data Symposium is Postponed until Spring 2019

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Breakthrough Discoveries, Disease Disparities, and Precision Medicine: A Computational Medicine Center Symposium on big data and disease disparities

The nature of Precision Medicine is quickly changing from "genome-facing" to “patient-facing.” Technological advances have been enabling breakthroughs on a number of fronts.  We are already experiencing these advances in our daily activities with the omnipresence of fitness trackers and of health record graphs that are available to consumers through the likes of Apple, 23andme, Fitbit, etc.  An analogous revolution is in the making on the basic research end of things. Research work in the last several years at Jefferson's Computational Medicine Center (CMC) has broken new ground in this regard.  The CMC's researchers have been trailblazing in this regard by making and reporting many discoveries that redefine the very concept of disease. By analyzing data from thousands of healthy individuals and patients, the CMC team has uncovered numerous novel regulatory molecules and showed that their abundance profiles depend on an individual's sex, population origin, and race/ethnicity as well as on tissue, tissue state, and disease. Moreover, the team showed that these molecules regulate important genes differentially by sex, race/ethnicity, etc. in cancers with known disparities whose molecular underpinnings had remained elusive until now.  The CMCs team's findings are beginning to provide much needed mechanistic explanations to observations that have been appearing in the literature in recent years by other teams. 

The symposium will place emphasis on how, going forward, one must take into account attributes of a patient whose role in the onset and progression of disease had not been appreciated until now.

Through a series of interconnected presentations, this symposium will present these emerging findings and put them in the context of understanding disease disparities, and designing better diagnostics and novel therapeutics.

At this 1.5-day symposium the attendees will receive specific examples of how these new molecules can be used to implement accurate diagnoses and improved prognoses. And will hear novel opportunities to create powerful therapeutics.  In both cases, i.e. diagnostics and therapeutics, the attendees will learn how to use computation and existing tools to identify molecules of interest that they can then pursue experimentally.



This course is designed for all primary care and specialists working in breast cancer, prostate cancer, lung cancer, bladder cancer medicine, and allied health professionals.




Additional information
Jefferson Content Development By: 
Sidney Kimmel Medical College (SKMC)
Thomas Jefferson University Hospital (TJUH)
Content Areas: 
Disparities in Healthcare
Course Format: 
Live Conference
Course summary
Available credit: 
  • 6.50 AMA PRA Category 1 Credit
  • 6.50 Attendance
Course opens: 
Course expires: 
Event starts: 
11/07/2018 - 6:00pm EST
Event ends: 
11/08/2018 - 3:30pm EST

Preliminary Program Agenda & Learning Objectives

For more course information, please view the preliminary program agenda and learning objectives.


Connelly Auditorium, Dorrance H. Hamilton Building
1001 Locust Street
Philadelphia, PA 19107
United States

For information regarding parking and directions please visit: 

Parking is available in the Dorrance H. Hamilton Building (entrance on 11th Street).  Discounts are not available.


The nearest hotel to Thomas Jefferson University Campus is the Holiday Inn Express Midtown located at 1305 Walnut Street.

Holiday Inn Express Midtown
1305 Walnut Street
Philadelphia PA, 19107
Reservations: 215-732-2022
Rates: $134 special hospital/university rate

No extra person charge. Includes complimentary breakfast, free access to wireless internet and onsite fitness center. Parking is $27 per day (with in and out privileges).

For additional hotels in the area, that also offer a Jefferson rate, please visit:


Featured Keynote Lecturer - Tiffany Wallace, PhD 
Wednesday, November 7, 2018
Tiffany Wallace is a Program Director in the Office of the Director of the NCI’s CRCHD since 2014. In this role, Dr. Wallace contributes to CRCHD’s programmatic efforts to strengthen NCI’s cancer health disparity research portfolio, encompassing basic, clinical, translational, and population-based research. Additional roles include contributing to the grant management of basic cancer research in cancer health disparities and representing CRCHD in the NCI’s Provocative Questions Initiative. Prior to joining NCI, Dr. Wallace was an Oncology Scientist at Human Genome Sciences (HGS), a biopharmaceutical corporation. Dr. Wallace received her Ph.D. in biomedical sciences from the University of Florida in Gainesville. She completed her postdoctoral training in the Laboratory of Human Carcinogenesis at NCI, where she conducted basic and translational research that provided novel insights on the role of biological factors as they contribute to cancer health disparities. Her research included identification of biomarkers of aggressive disease in prostate and breast cancers, with a focus on variations between different racial/ethnic groups.
To view all faculty, click here  
All faculty at continuing educating activities for nurses, physicians and allied health professionals are required to disclose to the audience:


  1. Any significant financial relationships with the manufacturer(s) of any commercial products, goods or services
  2. Any unlabeled/unapproved uses of drugs or devices discussed in their presentations.


Such disclosures will be made in writing in the course presentation materials. ​Jefferson Conflict of Interest resolution process may result in changes to the program agenda.



Sidney Kimmel Medical College at Thomas Jefferson University is accredited by the ACCME to provide continuing medical education for physicians.  Sidney Kimmel Medical College at Thomas Jefferson University designates this live activity for a maximum of 6.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The American Academy of Physician Assistants accepts AMA PRA Category 1 Credit(s)™. (

Available Credit

  • 6.50 AMA PRA Category 1 Credit
  • 6.50 Attendance


Please login or register to take this course.

The Big in Big Data Symposium is Postponed until Spring 2019

Click here to be notified of the new date


There is no registration fee for this course.  To enroll click Continue button. 



  • Pre-registration ends Monday, November 5, 2018. Onsite registration will be accepted.

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